Prognostic indicators in an aggressive pituitary Crooke's cell adenoma.
نویسندگان
چکیده
OBJECTIVE To investigate prognostic indicators in an aggressive Crooke's cell adenoma of the pituitary. METHODS The surgically removed tumor was studied by histology, immunohistochemistry and transmission electron microscopy. RESULTS An aggressive invasive sellar tumor removed by repeated surgeries from a 43-year-old woman with pituitary related Cushing's disease was classified as a Crooke's cell adenoma of the pituitary. The application of several cell proliferation markers confirmed the aggressive nature of the tumor. CONCLUSIONS The investigation of the present case provides additional evidence that pituitary Crooke's cell adenomas may possess aggressive behavior.
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ورودعنوان ژورنال:
- The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
دوره 32 4 شماره
صفحات -
تاریخ انتشار 2005